'You will find RUNONCE.EXE as a startup entry rather than as a background task. RUNONCE is the Microsoft 'Run Once' Wrapper. It is a program which developers can use as part of their installation procedures to ensure, for example, that after the first reboot post the installation of the software, some additional configuration program is run to complete the installation, and once only.
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It is not uncommon for a RUNONCE startup entry to be left behind after it has run once. Therefore, if you find a RUNONCE.EXE entry in your startups, reboot your PC¥ if it is still there after reboot, then you can safely disable it or delete it on the Startups tab.'
Source: http://searchtasks.answersthatwork.com/tasklist.php?File=RunOnce